Seroquel is an anti-psychotic medication available only by prescription. Seroquel is the trade-name for the generic drug Quetiapine Fumarate.
Seroquel is used in the treatment of schizophrenia to control delusions, hallucinations, thought problems and difficulties connecting with reality. Seroquel may also be prescribed on a short-term basis for the treatment of mania associated with bipolar disorder.
Seroquel dosage amounts vary depending on the patient's condition and response to medication. Some patients find a relatively low dose to be effective, while others will require a much higher dose. To find the appropriate dosage for an individual, the prescribing doctor will start with a low dose and increase gradually until the desired result is achieved.
Dosage for Schizophrenia
Usually, dosages of Seroquel for the treatment of schizophrenia range from between 300 and 400 milligrams per day. This dose is divided into two or three small doses. For some patients, a low dose of 150 mg proves effective; some may exceed 400 mg, but rarely will a prescription be for more than 750 mg daily, and more than 800 mg per day has not been tested for safety. Dosing starts low and increases over a four day period to find the optimal dose. The introductory dosing schedule usually follows this protocol:
• 25 mg twice on day 1
• Gradual daily increase by 25 to 50 mg for days 2-4 (taken in 2 or 3 daily doses)
• Increases by 25-50 mg every 2 days if needed after day 5
If a dose is missed it should be taken as soon as remembered, but not if it is close to the time for the next dose. Doses should never be doubled in an attempt to catch up a missed dose.
Dosing schedules for both schizophrenia and bipolar disorder may be lowered and made more gradual if patients suffer from liver disease and/or side effects.
Seroquel can interact with other medications and herbal remedies and supplements, so it is important to report all herbal, OTC, and prescribed medications to the patient's doctor. Seroquel can also cause and exacerbate certain medical conditions, and does carry a potential for side effects, so it is necessary to report all conditions (new or previously existing) to the prescribing doctor.
Seroquel should be stored at room temperature (ideally, 77 degrees), and kept away from heat and moisture. It is very important to keep Seroquel away from pets and especially children.
Seroquel, the trade name for the prescription anti-psychotic drug Quetiapine Fumarate, is used in the treatment of a range of mental disorders.
Specifically, Seroquel is used most often in the treatment of schizophrenia and bipolar disorder, or related disorders where there is a loss of reality/personality, and/or depression experienced. Seroquel effectively treats the manic phase of manic-depression, and may also be used to treat bipolar disorder in remission and bipolar I disorder (most recent episode mixed).
Dosing for Seroquel differs for each patient, and is increased gradually to determine optimal effective dosages. The increase generally takes place over 4 to 6 days until the desired effectiveness is achieved, under the close supervision of a medical doctor.
Seroquel Side Effects
Seroquel can be very dangerous if taken incorrectly, so it is important to follow the doctor's prescription instructions. Seroquel also carries a risk of side effects and allergy (as all drugs do). Any new symptoms or discomforts should be reported to the prescribing doctor right away. Seroquel side effects include:
• Constipation, abdominal pain
• Drowsiness, dizziness, tiredness
• Sluggish movement
• Stomach pain and nausea
• Rapid or irregular heartbeat
• Infection (characterized by fever, sore throat)
• Trouble swallowing
• Vision changes
• Muscle spasms, uncontrollable movements
• Nasal inflammation, sinus congestion
Mood changes and mental difficulties such as anxiety, depression, and/or thoughts of suicide may also occur. Patients must consult their doctor immediately if these are experienced.
While unlikely, males taking Seroquel may experience lasting (more than 4 hours) and painful erections. This may result in a permanent, serious condition; if this occurs, stop taking Seroquel and seek medical attention immediately.
Seroquel side effects are most common during initial treatment; the potential for side effects lessens as the protocol is continued. This is part of the reason doses are increased gradually (side effects are minimized with gradual dose increases).
While rare, Seroquel use may cause additional medical conditions, such as:
• Tardive Dyskinesia (may be permanent in some cases). Symptoms of this condition include abnormal and/or uncontrollable movements, especially of the face, mouth, arms, and legs.
• Neuroleptic Malignant Syndrome (serious, but rarely fatal). Characterized by muscle stiffness, high fever, profuse sweating, rapid heartbeat, mood change, and increase or decrease in urination.
Either condition can be serious, and patients should consult their doctor immediately if any of these symptoms are experienced.
Allergic reactions are rare with Seroquel, but are possible. Patients should report allergy symptoms (such as hives, itching, swelling, and breathing difficulties) to their doctor.
Seroquel may affect and/or be affected by other medications and medical conditions. It is important to report all medications (prescription, herbal, and OTC) to the prescribing doctor, as well as provide a complete medical history, including all previous and currently experienced medical conditions.
Additional Seroquel Drug Resources
Seroquel Information from Drugs.com
Seroquel (Quetiapine Fumarate) drug description
quetiapine (Seroquel) - drug class, medical uses
MedlinePlus Drug Information: Quetiapine
Seroquel (Quetiapine Fumarate) drug indications and dosage
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